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10 giugno 2014

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ResultsCharacterization of the phosphorylation profile of sMyBP C in the mouse fast twitch FDB muscle in health and dystrophyOur recent studies have demonstrated that sMyBP C encompasses a family of phosphoproteins with mSer 59 and mSer 62 phosphorylated by PKA, mThr 84 phosphorylated by PKC, and mSer 204 phosphorylated by both PKA and PKC11. Nike Air Max Goedkoop sac a dos fjallraven To study the phosphorylation profile of sMyBP C in fast twitch skeletal muscles in response to different (patho)physiological stressors, such as aging and disease, we selected the mouse FDB muscle because of the abundant expression of several sMyBP C variants9,10. Nike Air Max 2017 Heren zwart nike trainers sale We produced lysates from young (2 months) and old (14 months) wild type and mdx FDB muscles, which were analyzed by conventional and phosphate affinity gel electrophoresis and subsequent immunoblotting. Kanken No.2 Fjallraven Kanken Kids

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